This new sixth edition of "Burger's Medicinal Chemistry and Drug Discovery" offers several new and unique features. For the first time, an online version of this major reference work will offer updated content from the print edition and easy access. For the first time, all volumes are structured entirely according to content and published simultaneously to provide broad coverage of medicinal chemistry and drug discovery for new or experienced medicinal chemists, biologists, pharmacologists and molecular biologists. This includes a current and global perspective of drug design, and drug development.With expanded content from 69 chapters to over 100 chapters, this sixth edition of "Burger's Medicinal Chemistry and Drug Discovery" includes more than 50 percent new material. An entire section has been dedicated to cancer research. Areas included are those at the foreground of life science, including: proteomics; genomics; bioinformatics; combinatorial chemistry; high-throughput screening; blood substitutes; allosteric effectors as potential drugs; COX inhibitors; statins; high-throughput pharmacology and more.The new sixth edition of "Burger's Medicinal Chemistry and Drug Discovery" is a Memorial Edition to Professor Alfred Burger who published this major reference work in the first edition as "Medicinal Chemistry" in two volumes in 1951. Dr. Burger's research focused on analgesics, antidepressants and chemotherapeutic agents. He is one of the few academicians to have a drug, designed and synthesized in his laboratories and brought to market. Dr. Burger's contribution to the fields of medicinal chemistry and drug discovery are well renowned and documented. He received the Louis Pasteur Medal of the Pasteur Institute and the American Chemical Society Smissman Award.