Contributors from the United States, Canada, and Australia, working in university-based and community-based environments and for divergent communities present specific experiences in the fight against HIV/AIDS. They share stories of shifting paradigms and challenging norms, and of seeking and finding innovation. The topics examined include the struggle for meaning and power in HIV/AIDS education, HIV prevention workers and injection drug users, community-based research, grassroots response to HIV/AIDS in Nova Scotia, sex workers and HIV/AIDS education, and the Tuskegee Syphilis Study and legacy recruitment for experimental vaccines. By examining HIV/AIDS through an adult education lens, we gain insights into how communities (and governments) can respond quickly and effectively to emergent health issues and other issues linked to marginalization. This is the 105th issue of the quarterly report series "New Directions for Adult and Continuing Education".