Alejandro Jodorowsky (also known as Alexandro Jodorowsky) is a Chilean film and theatre director, screenwriter, playwright, actor, comic book writer, author, poet, mime, musician, and spiritual guru. He is best known for his avant-garde, cult films, such as "El Topo," a midnight movie favorite.

Jean Giraud aka Mœbius was a French artist, cartoonist, and writer, who worked in the Franco-Belgian bandes dessinées tradition. Giraud earned worldwide fame, predominantly under the pseudonym Mœbius, which he used to create a wide range of science fiction and fantasy comics in a highly imaginative and surreal, almost abstract style. Esteemed by Federico Fellini, Stan Lee and Hayao Miyazaki, among many others, he is considered as the most influential bande dessinée artist, and a continued influence to filmmakers and artists around the world.

John Difool, a low-class detective in a degenerate dystopian world, finds his life turned upside down when he discovers an ancient, mystical artifact called "The Incal." Difool’s adventures will bring him into conflict with the galaxy’s greatest warrior, the Metabaron, and will pit him against the awesome powers of the Technopope. These encounters and many more make up a tale of comic and cosmic proportions that has Difool fighting for not only his very survival, but also the survival of the entire universe.