When the world feels complicated, knitting is the perfect escape - follow the instructions and you end up with exactly what you want and expect. Life on the other hand doesn't come with a pattern. Kathleen, Sari and Lucy are close friends stumbling their way into adulthood, Kathleen is beautiful, flighty and lives off her famous actress sisters. Lucy once wanted to be a vet but instead became a scientist who dissects rats. Sari works at an autism clinic, providing the support her own autistic brother never got. The girls meet once a week to knit and talk - and now they need these get-togethers more than ever. Cut off financially from her family, Kathleen sets out to seduce her wealthy boss. Lucy finds herself torn between emotion and reason when her lab is attacked by animal rights activists and the bully who tormented Sari's brother now desperately needs her help. The girls forge their way in a world of tough choices, drawing strength from their friendship. Along the way they fall in love, they make mistakes, they get drunk, they have sex, they go shopping, they laugh, they cry...and they knit.