The third edition of this highly successful and established handbook has been completely revised and considerably extended, making it unrivaled in the timeliness and comprehensiveness of the information presented. This new edition runs to two volumes, with added chapters or sections covering: - New and important applications of ion chromatography in the life sciences, such as the analysis of proteins, nucleic acids, amino acids or carbohydrates. - New instrumentation that meets the demand for miniaturization and reduced analysis times. - Coupling of ion chromatography to mass-spectrometric or inductively coupled plasma detectors - Validation of ion-chromatographic methods, which is important for quality assurance The author has played a major role in the development of ion chromatography and a alongside his industrial post -- has been appointed as visiting professor at the University of Innsbruck, one of the prominent centers of chromatography research in the world.