Silicon-mediated Transformations of Functional Groups

出版者:John Wiley & Sons Inc

作者:Vorbrueggen, Helmut

页数:378

出版时间:2004-11

价格:224.00 元

装帧:HRD

isbn号码:9783527306688

In the first work to comprehensively cover this all-important topic, the recognized expert Helmut Vorbr?provides both organic and bioorganic chemists with much new and valuable information for preparative synthesis. Although every organic chemist may be familiar with different aspects of silylation for the protection of functional groups, this book covers the concept of protection while simultaneously silylating-activating various functional groups, such as amides and ureas. This novel methodology opens thus numerous synthetic pathways while effecting the elimination of water in it volatile persilylated form under rather mild reaction conditions, which are often advantageous compared to conventional methods. The compact form and clear structure of this monograph make this a long-awaited ready reference. From the contents: Introduction Techniques of Preparative Silylations-Desilylations Preparation and Properties of Siliconoxy-Leaving Groups Reactions of Free and Derivatized Carboxylic Acids and Carbon Dioxide Reactions of Aldehydes and Ketones Reactions of Alcohols, Ethers and Epoxides Reaction of N-O Systems Reactions of S-O and Se-O Systems Cyclizations and Ring Enlargements Base and Acid-Catalyzed as well as Thermal Eliminations of Trimethylsilanol. Peterson Reactions Formation of Carbon-Phosphorous Double- and Triple Bonds Reductions and Oxidations Dehydration-Activation as well as Silylation of Inorganic and Organic Salts and Metalorganic Compounds Formation of Polymers