The story follows a number of Jewish partisans and resistance fighters as they struggle to survive and sabotage the German war machine behind Nazi lines during World War II, starting in eastern Russia and ending in Milan.

The book's chief protagonist, Mendel Nachmanovich Dajcher, worked as a watch repairer before joining the Red Army, where he fought in the artillery. While he is at war, his wife and shtetl are massacred by a German Einsatzgruppe. In the midst of battle, he loses his regiment, becomes disoriented and is overtaken by the front, separated from and unsupported by Soviet forces.

His life thereafter is an odyssey through the "partisanka," the motley partisan movement, which includes Russians, Jews, Lithuanians and Poles. About halfway through the book, Mendel and his companion from the first chapter, Leonid, fall in with a group of Jewish resistance fighters called the gedalistas, after their leader: Gedale.

With them, Mendel traverses Poland and, overtaken by the victorious Soviets, enters defeated Germany. From there, the group aims for Italy, dreaming of making the aliyah to Palestine to take part in the Zionist project of reclaiming a Jewish homeland.