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发表于2025-01-07

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出版者:Informa HealthCare

作者:Robert C. Jackson

出品人:

页数:256

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出版时间:1996-07-23

价格:USD 229.95

装帧:Hardcover

isbn号码:9780849376825

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Computer Techniques in Preclinical and Clinical Drug Development 2025 pdf epub mobi 电子书图书描述

It is estimated that 80 to 90% of drugs under development never make it to the marketplace due to insufficient clinical activity, unacceptable toxicity, rapid appearance of drug resistance, or other factors that should be, at least partially, predictable from preclinical testing. This new text asks the question, "How can we use computational methods to improve the success rate in drug development?" Computer Techniques in Preclinical and Clinical Drug Development shows how modeling makes it possible to extract the maximum amount of information and predictive value from preclinical data. Computer modeling methods from the areas of pharmacokinetics, pharmacodynamics, cytokinetics, and inhibition kinetics of multi-enzyme pathways are all discussed in this unique reference source.

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