This book constitutes the refereed proceedings of the 11th International Conference on Model Driven Engineering Languages and Systems, MoDELS 2008, held in Toulouse, France, during September 28-October 3, 2008. The 58 revised full papers presented were carefully reviewed and selected from 271 submissions. The book also contains three keynote speeches and contributions to workshops, symposia, tutorials and panels at the conference. The papers are organized in topical sections on Model Transformation: Foundations; Requirements Modeling; Domain-Specific Modeling; Model Transformation: Techniques, Composition and Analysis of Behavioral Models; Model Comprehension; Model Management; Behavioral Conformance and Refinement; Metamodeling and Modularity; Constraints; Model Analysis; Service-Oriented Architectures; Adaptive and Autonomic Systems; Empirical Studies; Evolution and Reverse Engineering; Modeling Language Semantics; Dependability Analysis and Testing; Aspect-Oriented Modeling; Structural Modeling;and Embedded Systems.