Clinical Epidemiology

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出版者:
作者:Grobbee, Diedrerick E., M.D., Ph.D./ Hoes, Arno W., M.D., Ph.D.
出品人:
頁數:413
译者:
出版時間:2008-3
價格:$ 143.45
裝幀:
isbn號碼:9780763753153
叢書系列:
圖書標籤:
  • 臨床流行病學
  • 流行病學
  • 醫學統計
  • 循證醫學
  • 研究方法
  • 健康科學
  • 公共衛生
  • 臨床研究
  • 疾病風險
  • 診斷
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具體描述

New Edition Available 7/1/2013 In the current era of evidence-based medicine, clinical epidemiology is increasingly recognized as an essential tool in the critical appraisal of available evidence and the design of new studies. Clinical Epidemiology: Principles, Methods, and Applications for Clinical Research is a comprehensive resource that introduces the reader to the basics of clinical epidemiology and explores the principles and methods that can be used to obtain quantitative evidence on the effects of interventions and on the diagnosis, etiology, and prognosis of disease. The everyday challenges of clinical research and the quantitative knowledge required to practice medicine are also examined, making this book a valuable reference for both graduate and undergraduate students in medicine and related disciplines, as well as for professionals involved in the design and conduct of clinical research. Key features: * Worked-out examples from daily clinical practice included in all sections. * Relevant clinical research that can be used as exercises. * Several chapters devoted to research assessing the main and adverse effects of interventions, including introductions to clinical trials. * Common study designs (such as meta-analyses, case-control studies and randomized trials), as well as elementary data-analytical issues. Principles and Methods of Clinical Epidemiology explores the challenges clinicians face in daily practice and the quantitative knowledge required to practice medicine. An important distinction is made between research directed at unraveling causality (notably etiologic research and studies addressing the effects of interventions) and descriptive research aimed at predicting the presence (diagnostic research) or consequences of disease (prognostic research). The book is intended for both the users of clinical research findings (i.e. those practicing medicine and related disciplines such as pharmacy, health sciences, nursing sciences, and veterinary medicine) and those involved in the design and conduct of applied clinical research. Also future "users" and "do-ers" of applied clinical research (notably undergraduate students and PhD fellows in medicine and related disciplines) will benefit from the book. Teachers of clinical epidemiology will find the book a valuable reference with their classes.

《Clinical Epidemiology》是一本全麵而深入的學術著作,係統地介紹瞭臨床流行病學領域的重要概念、理論和方法。這本書以嚴謹的研究方法和豐富的實例為基礎,幫助讀者全麵理解該學科的核心內容。內容涵蓋從數據收集與分析到研究設計、統計方法及其實際應用的各個環節,旨在為初學者提供堅實的理論基礎,同時也為有經驗的專業人士更新知識儲備。 書中首先係統地講解瞭流行病學的基本原理和核心概念,詳細介紹瞭如何設計研究以評估疾病發生、分布及其影響。這部分內容不僅涵蓋傳統的研究方法,還結閤現代數據科學技術,對新興的統計分析工具進行深入探討。此外,該書還特彆強調瞭數據質量的重要性,通過實際案例說明如何識彆和解決數據中的偏差與限製,確保研究結果的可靠性。 在研究設計部分,書中詳細解析瞭常見實驗設計如隨機對照試驗、觀察性研究以及乾預研究的具體步驟和注意事項。讀者可以通過這些內容瞭解如何選擇閤適的設計,避免常見的方法學誤區,並提升研究的科學性與有效性。 書中還深入探討瞭統計分析在流行病學中的應用,包括描述性統計、假設檢驗、迴歸分析等技術手段。這些部分不僅幫助讀者掌握基本的數據處理技能,還引導他們理解這些方法如何支持疾病發生率的比較、風險因子的識彆以及預測模型的構建。 另一重要內容是對流行病學數據源與工具的介紹,包括流行病學軟件使用指南和文獻檢索技巧。這為讀者提供瞭實用的資源,幫助他們在實際工作中高效地獲取並分析必要的信息。書中還特彆強調瞭倫理考量的重要性,在研究設計、數據使用及成果發布環節,詳細討論瞭如何遵循科研誠信原則。 此外,該書還包括大量案例和實例,通過真實世界的場景,讓讀者能夠更直觀地理解理論知識的實際應用。這些案例涵蓋不同地區、不同疾病類型以及各種研究方法,幫助讀者在思考復雜問題時提供清晰的參考框架。 總的來說,這本書不僅是一份內容豐富的學術指南,更是一個全麵指導讀者從理論到實踐的學習工具。它為希望深入研究或應用流行病學知識的專業人士提供瞭寶貴的資源,幫助他們建立科學思維、提升分析能力,並在各個層麵上做齣更具影響力的研究和決策。該書的結構清晰,內容詳實,使其成為臨床流行病學領域中不可或缺的一部分。

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