This edited book makes an attempt to cover a wide range of both current basic research and applied clinical topics related to skeletal muscle damage and repair mechanisms and their application. The book is divided into three sections comprising related chapters, each written by an internationally acclaimed researcher or research group who are experts in their field. The first section reviews current research and covers the current understanding of issues related to the mechanisms of muscle damage, physiological responses to damage and subsequent muscle repair mechanisms. The second section examines muscle damage and repair mechanisms and issues in specific populations including older adults and special populations.The final section takes a critical look at various interventions that have been used or advocated for the treatment of muscle damage. It covers current understanding of the potential physiological mechanisms of these interventions and the evidence for their effectiveness.