There is widespread recognition that globalization is changing the world around us, but so far there has been no systematic analysis of how it is impacting on human health. Such impacts are diverse, encompassing global economic, political, sociocultural, technological and environmental changes. Globalization and Health presents a clear conceptual framework for understanding these varied impacts, focused on spatial, temporal and cognitive dimensions of global change. A broad range of literature across different disciplines is drawn upon to illustrate this. Kelley Lee demonstrates that globalization, in its current form, is having both positive and negative consequences, creating new patterns of health and disease in population groups across the world. These changes are posing fundamental challenges to the way that we think about the determinants of health and health outcomes. More attention is needed to ensure that current forms of globalization become more equitable, sustainable and guided by appropriate forms of governance.