This volume provides an in-depth exploration of two key processes in communication research: uncertainty and information regulation. These topics have been an integral part of communication research for many years, and have experienced an explosion of scholarly attention in the past decade. The processes are central to several disciplines (e.g., communication, psychology) and sub-disciplines (e.g., health psychology & communication, family communication, interpersonal communication, risk communication & terrorism), but still focus specifically on interpersonal relationships.Published work has been scattered throughout journals and book chapters. This volume will be the first collection to provide both breadth and depth on the theories and applied research in these areas, and it promises to be a widely used resource that advances knowledge and contributes to continued growth in understanding these important processes. Contributors include the best-known scholars working in communication studies, many of them senior academics, and the volume promises to be an exceptional collection of theory and research on an increasingly important area of communication study. Its breadth of coverage makes it stand out in the marketplace.