Nucleic acids are the fundamental building blocks of DNA and RNA and are found in virtually every living cell. Molecular biology is a branch of science that studies the physicochemical properties of molecules in a cell, including nucleic acids, proteins, and enzymes. Increased understanding of nucleic acids and their role in molecular biology will further many of the biological sciences including genetics, biochemistry, and cell biology. "Progress in Nucleic Acid Research and Molecular Biology" is intended to bring to light the most recent advances in these overlapping disciplines with a timely compilation of reviews comprising each volume. This book reviews the research and aids the reader in understanding the mechanisms of protein misfolding. This helps to understand diseases and guide researchers to design therapeutic strategies. It highlights important topics and presents a thorough review eliminating searching through many journal articles.