Bryan Lee O'Malley (born 21 February 1979) is a Canadian cartoonist. His first original graphic novel was Lost at Sea (2003), and he is currently working on (and best-known for) the six-volume Scott Pilgrim series (2004 to present). All of his graphic novels thus far have been published by Portland, Oregon-based Oni Press. He is also a songwriter and musician (as Kupek and formerly in several short-lived Toronto bands).

Prior to having his own material published, O'Malley illustrated the Oni Press miniseries Hopeless Savages: Ground Zero, written by Jen Van Meter. He also lettered many Oni Press comics, including the majority of Chynna Clugston's output between 2002 and 2005.

In 2005, O'Malley won the Doug Wright Award for Best Emerging Talent and was nominated for 3 Harvey Awards. In 2006, he was nominated for an Eisner Award for 'Best Writer/Artist - Humour', and won 'Outstanding Canadian Comic Book Cartoonist (Writer/Artist)' in the Joe Shuster Awards. He was also nominated for two Eagle Awards and for a second Doug Wright Award.

He currently lives near the Halifax Regional Municipality, Nova Scotia, with his wife, cartoonist Hope Larson.