Chossudovsky has taught as visiting professor at academic institutions in Western Europe, Latin America and Southeast Asia, has acted as economic adviser to governments of developing countries and has worked as a consultant for international organizations including the United Nations Development Programme (UNDP), the African Development Bank, the United Nations African Institute for Economic Development and Planning (AIEDEP), the United Nations Population Fund (UNFPA), the International Labour Organization (ILO), the World Health Organisation (WHO), the United Nations Economic Commission for Latin America and the Caribbean (ECLAC). In 1999, Chossudovsky joined the Transnational Foundation for Peace and Future Research as an adviser.[3]

Chossudovsky is past president of the Canadian Association of Latin American and Caribbean Studies. He is a member of research organisations that include the Committee on Monetary and Economic Reform (COMER), the Geopolitical Drug Watch (OGD) (Paris)and the International People's Health Council (IPHC).[3]

He is an active member of the anti-war movement in Canada, and has written extensively on the war in Yugoslavia. After the September 11 terrorist attacks he has also been involved in highlighting the historical relationship between the US government, Bin Laden and Al Qaeda. He is a frequent contributor to Le Monde diplomatique, Third World Resurgence and Covert Action Quarterly.[4] His publications have been translated into more than twenty languages. His latest book is titled America's "War on Terrorism".

He is editor for the Centre for Research on Globalization, which operates a website at globalresearch.ca. The Centre for Research on Globalization states to be "committed to curbing the tide of "globalisation" and "disarming" the New world order".