Syd Hoff (September 4, 1912 Bronx, New York – May 12, 2004) was a Jewish-American cartoonist and children's book author. Although best known for his classic early reader Danny and the Dinosaur, his cartoons appeared in a multitude of genres, including advertising commissions for such companies as Eveready Batteries, Jell-O, S.O.S Pads, Rambler, Ralston Cereal and more.

While Hoff was still in high school, Milt Gross, a popular 1930s cartoonist, told him at an assembly that "Kid, someday you'll be a great cartoonist!" At 16, he enrolled at the National Academy of Design in New York City. At 18, he sold his first cartoon to The New Yorker, and would sell a total of 571 of them to the publication from 1931 to 1975. Hoff became known for his cartoons, in The New Yorker, depicting tenements and lower-middle class life in the city.

Hoff drew two long-running syndicated comic strips: Tuffy (1939–1949) and Laugh It Off (1958–1978). One of Hoff's recurring characters, a walrus-mustached man, eventually appeared as the father in his daily Tuffy, done for the King Features Syndicate from 1940 to 1950.

His cartoons have appeared in a variety of publications including, the New Yorker, Esquire, Look magazine. He was also the host of a television show, Tales