Dorothy Bryant is a native San Franciscan, the daughter of immigrants from northern Italy. She attended public schools in the Mission District, then San Francisco State University, completing a BA in music (1950) and an MA in creative writing (1964). From 1953 to 1976 she taught music and English in Bay Area high schools and colleges, spending the most time at Contra Costa College, after moving to Berkeley in 1964. She began writing fiction and articles in 1960.

Mei-li Murrow, the illegitimate daughter of a Chinese prostitute and a white confidence man, is recreated as the medium "Madame Psyche" after she accidentally predicts the San Francisco earthquake of 1906. Although she wins fame and fortune as a medium, Mei-li seeks a truer spirituality, and embarks on a pilgrimage that takes her to the death-soaked Europe of the First World War, to a utopian commune in the Santa Cruz Mountains in the 1920s, to Depression-era migrant work camps and cannery strikes, and finally to the Napa State Hospital, where she finds wisdom and peace among the outcasts of the asylum.