This state-of-the-science reference provides valuable information on the pathophysiology and economic and social consequences of allergic skin reactions, as well as new treatments based on emerging concepts of skin disease pathobiology-addressing the epidemiology, mechanisms, occupational effects, environmental triggers, and quality-of-life concerns. Focuses on atopic dermatitis, urticaria, and allergic contact dermatitis, among other increasingly common skin disorders. Written by more than 35 leading researchers, Allergic Skin Disease reviews basic principles of the causes of allergic skin responses analyzes the role of key cell types, effector molecules, cytokines, mediators, chemokines, cell adhesion molecules, and immunogenetic mechanisms showcases the dynamics of adhesion molecules and the pathophysiology of pruritus examines clinical features of skin allergies, particularly regarding immune mechanisms that determine pathogenic course and outcome investigates behaviors of keratinocytes, dendritic cells and macrophages, fibroblasts, lymphocytes, granulocytes, and endothelial cells explores phototherapy, photochemotherapy, immunomodulatory therapy, and traditional antiinflammatory therapy for recalcitrant skin diseases discusses anaphylaxis and other allergic reactions to insect bites surveys demographism, vibratory angioedema, and other types of urticaria identifies allergic and infectious triggers of skin disease and more! Containing over 1800 bibliographic citations, Allergic Skin Disease is a must-read resource for dermatologists, allergists, immunologists, pharmaceutical and cosmetic chemists, internists, pediatricians, and graduate and medical school students in these disciplines.
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