Principles of Tissue Engineering is the widely recognized definitive resource in the field. The fourth edition provides an update on the rapid progress that has been achieved in tissue engineering, in areas including models, transplantation, gene therapy, and synthesis and control, all presented by the world's experts. The book is organized into more than 20 parts that cover the basics of tissue growth and development, approaches to tissue and organ design, and a summary of current knowledge by organ system. This edition adds more detailed focus on stem cells, and addresses new topics including bionics and brain-machine interface, organs-on-a-chip, immunology and inflammation, and blood components from stem cells. There is an additional section on tissue-engineered food and another on clinical experiences, topics that bring the research closer to popular relevance. It includes new chapters on biomaterial-protein interactions, nanocomposite and three-dimensional scaffolds, skin substitutes, spinal cord, vision enhancement, and heart valves. It offers expanded coverage of adult and embryonic stem cells of the cardiovascular, hematopoietic, musculoskeletal, nervous, and other organ systems. It features full color presentation throughout.