Walter Isaacson, a professor of history at Tulane, has been CEO of the Aspen Institute, chair of CNN, and editor of Time. He is the author of Leonardo da Vinci; The Innovators; Steve Jobs; Einstein: His Life and Universe; Benjamin Franklin: An American Life; and Kissinger: A Biography, and the coauthor of The Wise Men: Six Friends and the World They Made. Visit him at Isaacson.Tulane.edu.
发表于2024-11-07
The Code Breaker 2024 pdf epub mobi 电子书
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The bestselling author of Leonardo da Vinci and Steve Jobs returns with a gripping account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies.
When Jennifer Doudna was in sixth grade, she came home one day to find that her dad had left a paperback titled The Double Helix on her bed. She put it aside, thinking it was one of those detective tales she loved. When she read it on a rainy Saturday, she discovered she was right, in a way. As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.
Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned a curiosity of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions.
The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code.
Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids?
After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020. Her story is a thrilling detective tale that involves the most profound wonders of nature, from the origins of life to the future of our species.
roadtrip上听完了有声书 比预计的更有意思更drama crispr出来的时候 很多报道podcast采访 biotech/genes也hype很久了 但都知道了些皮毛 这本书听完才觉得真的懂了些 science确实是很competitive的field 特别是这些lab类的 发文章cycle还算快 就真的是分秒必争 同事之间的合作和竞争关系微妙 好奇如果有本从boston角度来讲(vs. Berkeley)会是怎么个态度 Isaacson很是细节之王 多少年前的事情 估计当事人都记不清楚了 他能写细致至极 feminism贯穿了整本书 最后几章讲gene editing moral的有点散
评分感觉看了一部宫斗剧?
评分除了学习科学知识 还借鉴得到成功科学家的品质 追求卓越注重合作然而又能严格管理自己的时间界限 生命科学的魅力 疫情初期紧锣密鼓的研究与疫苗开发 意外还有1984 vs. Brave New World这一对比重现 虽然有主POV CRISPR学术之争的叙述个人感觉尚且公正 希望能多收集一些行家线报实验室风云!
评分"Great Inventions come from understanding basic science"
评分这本书的写法太闷了,吸引人的反而是那些争议角色,比如口无遮拦的沃森,或者死捧弟子的Eric Lander,其他角色都立不起来。好在crispr周围的抓马就算遇到这种笔触也丝毫没有减少八点档特质。伦理部分非常浅,有大段丝毫没有建设性的“上帝”“自然”讨论,这都什么年代了。在我看来社交网络还邪恶得要死呢,但人家已经在这里了,好好拆分和针对性解决吧。有朝一日我一定能等来有个性有文笔还不谈上帝的生物学家重写这段往事的
The Code Breaker 2024 pdf epub mobi 电子书