Empire of Pain 2024 pdf epub mobi 电子书

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Empire of Pain 2024 pdf epub mobi 电子书著者简介

Patrick Radden Keefe is a staff writer at The New Yorker and the author, most recently, of the New York Times bestseller Say Nothing: A True Story of Murder and Memory in Northern Ireland, which received the National Book Critics Circle Award for Nonfiction, was selected as one of the ten best books of 2019 by The New York Times Book Review, The Washington Post, the Chicago Tribune and The Wall Street Journal, and was named one of the “10 Best Nonfiction Books of the Decade” by Entertainment Weekly. His previous books are The Snakehead and Chatter. His work has been recognized with a Guggenheim Fellowship, the National Magazine Award for Feature Writing and the Orwell Prize for Political Writing. He is also the creator and host of the eight-part podcast Wind of Change.

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发表于2024-12-23

Empire of Pain 2024 pdf epub mobi 电子书

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第一部分，感觉就是<Mad Men> 。一代犹太移民的儿子Arthur Sackler 从高中起就显示了非凡卓越的经商天赋，弄一个yearbook 人家高中生就能说服老师改成提成制，接广告拉赞助，财源滚滚风生水起。不愿意去放狗他的实际形象，宁可把在Madison Ave开广告公司，才华横溢风流倜...

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三代赛克勒家族，三代阿片类止痛药，上千亿身价，几千万人上瘾滥用，几十万人过量吸食致死包括演《断背山》的男主和歌手Prince，FDA、法官、媒体都拿这个家族没办法有的还同流合污，最后赛克勒家族还能保全财产全身而退，企业变成公有制继续生产致命药丸好赚钱补贴给受害者。这...

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I am floored. This is horrifying. I had to collect myself for a while before I could jot down anything. The level of depravity, greed and selfness is shocking. The fact that this is true history just knocks my socks off. The hair on the back of my neck was...

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出版者:Doubleday

作者:Patrick Radden Keefe

出品人:

页数:560

译者:

出版时间:2021-4-13

价格:USD 19.69

装帧:Hardcover

isbn号码:9780385545686

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Empire of Pain 2024 pdf epub mobi 电子书图书描述

A grand, devastating portrait of three generations of the Sackler family, famed for their philanthropy, whose fortune was built by Valium and whose reputation was destroyed by OxyContin, by the prize-winning, bestselling author of Say Nothing

The Sackler name adorns the walls of many storied institutions—Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, known for their lavish donations to the arts and the sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing a blockbuster painkiller that was the catalyst for the opioid crisis.

Empire of Pain begins with the story of three doctor brothers, Raymond, Mortimer and the incalculably energetic Arthur, who weathered the poverty of the Great Depression and appalling anti-Semitism. Working at a barbaric mental institution, Arthur saw a better way and conducted groundbreaking research into drug treatments. He also had a genius for marketing, especially for pharmaceuticals, and bought a small ad firm.

Arthur devised the marketing for Valium, and built the first great Sackler fortune. He purchased a drug manufacturer, Purdue Frederick, which would be run by Raymond and Mortimer. The brothers began collecting art, and wives, and grand residences in exotic locales. Their children and grandchildren grew up in luxury.

Forty years later, Raymond’s son Richard ran the family-owned Purdue. The template Arthur Sackler created to sell Valium—co-opting doctors, influencing the FDA, downplaying the drug’s addictiveness—was employed to launch a far more potent product: OxyContin. The drug went on to generate some thirty-five billion dollars in revenue, and to launch a public health crisis in which hundreds of thousands would die.

This is the saga of three generations of a single family and the mark they would leave on the world, a tale that moves from the bustling streets of early twentieth-century Brooklyn to the seaside palaces of Greenwich, Connecticut, and Cap d’Antibes to the corridors of power in Washington, D.C. Empire of Pain chronicles the multiple investigations of the Sacklers and their company, and the scorched-earth legal tactics that the family has used to evade accountability. The history of the Sackler dynasty is rife with drama—baroque personal lives; bitter disputes over estates; fistfights in boardrooms; glittering art collections; Machiavellian courtroom maneuvers; and the calculated use of money to burnish reputations and crush the less powerful.

Empire of Pain is a masterpiece of narrative reporting and writing, exhaustively documented and ferociously compelling. It is a portrait of the excesses of America’s second Gilded Age, a study of impunity among the super elite and a relentless investigation of the naked greed and indifference to human suffering that built one of the world’s great fortunes.

Empire of Pain 2024 pdf epub mobi 电子书

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Empire of Pain 2024 pdf epub mobi 用户评价

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我以為Book 1的stereotypical老白男發家史已經很讓人血壓飆升了，沒想到Book 2&3裡二代三代們的pathological-denial and accountability-avoiding真是歎為觀止的rage-inducing。我相信第一代進入製藥業的出發點是好的，第二代發明oxycontin的出發點是好的。但因為上市前的研究不足，以及aggressive advertising (no thanks to Arthur Sackler and his methods)導致現在opioid crisis這家人的作為 (or lack thereof)肯定是有直接關係的。書裡揭露出有問題的不僅是這家人，不僅是製藥業，不僅是資本，還有不作為的FDA、司法機構和法律漏洞

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"If there was one thing, apart from donating money, that the Sacklers knew how to do, it was sell opioids." 看这书让我感觉真心感觉FDA是个250，前一款opioid pain killer的专利期刚过，Sackler就发布一款新的止痛药并声称比之前那款更加不会导致上瘾，FDA居然也能审批通过。而且一个家族在作恶数个generation之后遭遇集体控诉还可以全身而退，完全没有对个人的任何处决，甚至还能照样带走几十个billion，资本对世界的控制真是可怕

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写了我非常喜欢的say nothing 的调查型作家Patrick Keefe去年的新书。非常详实的讲述了oxycontin的发家史。相当精彩。没想到我们这么常用的止痛药，在美国乃至全世界造成了这么严重的鸦片类药物滥用。有一个有趣的小知识居然是因为sterotype严重，医生不愿意给Africa-american开鸦片类药物的处方，结果黑人居然是最少滥用的人群。所以从一个侧面也说明，如果从处方严格管理控制，也是有效的吧。希望会有更多的RCT的结论。有声书由作者自己讲述，讲得还是非常精彩的。用词简单，情节丰富，非常推荐。时长18时7时。

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Empire of Pain 2024 pdf epub mobi 电子书